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Th细胞亚群在类风湿性关节炎治疗前后的临床意义

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摘要 目的探讨类风湿性关节炎患者外周血Th细胞亚群Thl、Th2、Thl7细胞的数量及Thl/Th2比值在治疗前后的变化,分析其在类风湿关节炎患者的作用及意义。方法选取43例类风湿性关节炎患者(观察组),另取正常体检者30例为对照组。采用流式细胞术检测在类风湿关节炎患者治疗前后Thl、Th2、Thl7细胞的数量及Thi/Th2比值。结果类风湿关节炎患者Thl细胞、Thl7细胞的数量以及Thi/Th2细胞比值均分别高于健康对照组(P〈0.05)。患者在治疗12周后,Thl细胞亚群阳性率亦明显降低,较治疗前差异有统计学意义;Th2细胞阳性率治疗前后差异无统计学意义。结论Th细胞亚群Thl、Th2、Thl7细胞的数量及Thi/Th2比值的变化在类风湿性关节炎患者中有重要的临床意义。
出处 《国际检验医学杂志》 CAS 2013年第B12期93-94,共2页 International Journal of Laboratory Medicine
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参考文献6

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