体外反搏对急性缺血犬动脉剪切应力影响的实验研究

AN EXPERIMENT STUDY OF THERAPENTIC MECHANISMAN ON MYOCARDIAL ISCHEMIA WITH EXTERNAL COUNTERPULSATION IN DOGS

为研究体外反搏对心肌缺血的治疗机理，分别测量在正常情况下、缺血１小时、缺血２小时、缺血１小时后反搏１小时、反搏２小时犬头臂干、颈动脉、胸主动脉、腹主动脉处的实时血流量，而后通过数学计算得出各处的实时剪切应力。结论是急性心肌缺血使各处动脉血管剪切应力的脉动性下降；体外反搏的作用可增加各处动脉剪切应力的脉动性。

Objective: To the effect of external counterpulsation on arterial shear stress in acute ischemia dpgs. Methods: Blood flows were measured at the arteria carotics, truncus brachiocephalics, thoracic aorta and desending aorta for chest-open dogs on the condition of pre-ischemia, one hour after ischemia, two hour after ischemia, one hour after EECP and two hours after EECP, shear stress were operated. The statistic results show that myocardial ischemia make phasic characteristics of shear stress fallen and EECP phasic characteristics of shear stress increased.