西沙必利治疗婴幼儿胃食管反流分析

Analysis of Cisapride for Infants Gastroesophageal Reflux

目的:评价西沙必利治疗婴幼儿胃食管反流(GER)的疗效。方法:将80例GER病儿随机分为2组,B组为西沙必利治疗组,C组为体位治疗组,取20例无症状儿为对照组(A组),观察指标取症状恢复时间,食管pH值,LESP检测变化。结果:西沙必利治疗GER疗效确实,B组总有效率(90.0％)与C组(60.0％)比较有显著性差异(P<0.01)。结论:西沙必利治疗GER确实有效,并无明显副作用。

Objective: To evaluate the efficiency of cisapride for infants gastroesophageal reflux(GER). Methods: Eighty ill infants were divided into two groups. Group B were treated with cisapride, group C were treated with children position, twenty asymptomatic infants as control group(group A). The symptom elimination time, esophageal pH monitoring and LESP were used to evaluate the efficacy. Results; The total efficient rate of group B and group C were 90 % and 60%, respectively, P<0.01. Conclusion: Cisapride for infant GER was effective and special side effects did not found.