巴西咖啡豆挥发性物质研究

Analysis on volatile components of Brazilian coffee beans

目的:对巴西咖啡豆中挥发性物质进行分析及比较研究。方法:采用水蒸气蒸馏法-气相色谱-质谱联用技术(SD-GC-MS)及顶空固相微萃取-气相色谱-质谱联用技术(HS-SPME-GCMS)对巴西咖啡豆挥发性成分进行定性分析,以峰面积归一化法计算各组分的相对百分含量。结果:通过SD-GC-MS和HS-SPME-GC-MS分析,分别确定了其中的26和49个成分,其中共有成分有8个,主要为5-甲基呋喃醛、愈创木酚、4-乙基愈创木酚、二糠基醚、棕榈酸等,占各自挥发性物质总量的34.3%和17.65%。结论:HS-SPME-GC/MS分析技术灵敏度高、选择性强,较SDGC/MS更有优势。

Superparamagnetic iron oxide nanoparticles （SPIONs） are one of the most versatile and safe nanoparticles in a wide variety of biomedical applications. In the past decades, considerable efforts have been made to investigate the potential adverse biological effects and safety issues associated with SPIONs, which is essential for the development of next-generation SPIONs and for continued progress in translational research. In this mini review, we summarize recent developments in toxicity studies on SPIONs, focusing on the relationship between the physicochemical properties of SPIONs and their induced toxic biological responses for a better toxicological understanding of SPIONs.