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利可君治疗宫颈鳞癌患者同步放化疗后骨髓抑制的临床观察 被引量:4

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摘要 目的观察利可君对宫颈鳞癌同步放化疗后骨髓抑制的情况。方法将96例宫颈鳞癌同步放化疗患者分成治疗组(同步放化疗联合利可君)和对照组(单纯同步放化疗组),观察两组患者粒细胞集落刺激因子(G-CSF)使用总量及均量、两组5次化疗前及第5次化疗后的白细胞(WBC),第1、4次化疗前及第5次化疗后的红细胞(RBC)、血红蛋白(HGB)和血小板(PLT)。结果与对照组比较,治疗组能明显减少化疗期间G-CSF平均用量,差异有统计学意义(<0.01);治疗组各期WBC计数均高于同期对照组,差异均有统计学意义(均<0.05)。结论利可君在宫颈鳞癌同步放化疗中有良好的防治WBC减少的作用。
出处 《现代实用医学》 2013年第11期1258-1260,共3页 Modern Practical Medicine
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参考文献7

  • 1Dubay RA,Rose PG,David MO.Evaluation of concurrent and adjuvant carboplatin with radiation therapy for locally advanced cervical cancer[J].Gynecologic Oncology,2004,94(1):121-124.
  • 2Higgins RV,Naumann WR,Hall JB,et al.Concurrent carboplatin with pelvic radiation therapy in the primary treatment of cervix cancer[J].Gynecologic Oncology,2003,89(3):499-503.
  • 3Lorvidhaya V,Chitapanarux I,Sangruchi S,eta 1.Concurrent mitomycin C,5-fluorouracil,and radiotherapy in the treatment of locally advanced carcinoma of the cervix:a randomized trial[J].Int J of Radiat Oncol Biol Phys,2003,55(5):1226-1232.
  • 4Pecorelli S,Zigliani L,Odicino F.Revised HGO staging for carcinoma ofthe cervix[J].Int J Gynaecol Obstet,2009,105(2):107-108.
  • 5Pecorelli S.Revised FIGO staging for carcinoma of the vulva,cervix,and endometrium[J].Int J Gynaecol Obstet,.2009,105(2):102-103.
  • 6Kirwan JM,Symonds P,Green JA,et al.A systemic review of acute and late toxicity of concomitant chemoradiation for cervical cancer[J].Radiother Oncol,2003,68(3):217.
  • 7胡群超,吴锦昌.宫颈癌同步放化疗研究现状[J].肿瘤基础与临床,2011,24(5):453-455. 被引量:16

二级参考文献32

  • 1Parkin DM,Bray F,Ferlay J,et al.Global cancer statistics,2002[J].CA Cancer J Clin,2005,55(2):74-108.
  • 2Kamangar F,Dores GM,Anderson WF.Patterns of cancer incidence,mortality,and prevalence across five continents:defining priorities to reduce cancer disparities in different geographic regions of the world[J].J Clin Oncol,2006,24(14):2137-2150.
  • 3Puget Sound Oncology Consortium,Swisher EM,Swensen RE,et al.Weekly emcitabine and cisplatin in combination with pelvic radiation in the primary therapy of cervical cancer:a phase Ⅰ trial of the Puget Sound Oncology Consortium[J].Gynecol Oncol,2006,101 (3):429-435.
  • 4Keys HM,Bundy BN,Stehman FB,et al.Cisplatin,radiation,and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage Ⅰ B cervical carcinoma[J].N Engl J Med,1999,340(15):1154-1161.
  • 5Morris M,Eifel PJ,Lu J,et al.Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer[J].N Engl J Med,1999,340(15):1137-1l43.
  • 6Peters WA 3rd,Liu PY,Barrett RJ 2nd,et al.Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix[J].J Clin Oncol,2000,18(8):1606-1613.
  • 7Whitney CW,Sause W,Bundy BN,et al.Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage Ⅱ B-ⅣA carcinoma of the cervix with negative paraaortic lymph nodes:a Gynecologic Oncology Group and Southwest Oncology Group study[J].J Clin Oncol,1999,17 (5):1339-1348.
  • 8Rose PG,Bundy BN,Watkins EB,et al.Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer[J].N Engl J Med,1999,340(15):1144-1153.
  • 9Chemoradiotherapy for Cervical Cancer Meta-Analysis Collaboration.Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer:a systematic review and meta-analysis of individual patient data from 18 randomized trials[J].J Clin Oncol,2008,26(35):5802-5812.
  • 10Eifel PJ.Concurrent chemotherapy and radiation therapy as the standard of care for cervical cancer[J].Nat Clin Pract Oncol,2006,3(5):248-255.

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