海芋化学成分研究

Study on Chemical Constituents of Alocasia macrorrhiza

目的 研究天南星科植物海芋的化学成分.方法 利用90％乙醇提取,聚酰胺柱层析、硅胶柱层析等方法分离纯化化合物,并通过理化性质和波谱数据鉴定其结构.结果 从海芋中分离并鉴定了6个化合物,分别是1,2-dihydro-6,8-dimethoxy-7-hydroxy-1-（3,5-dimethoxy-4-hydroxyphenyl）-N1,N2-bis-[2-（4-hydroxyphenyl）ethyl]-2,3-naphthalene dicarboxamide（1）、cannabisin F（2）、棕榈酸（3）、棕榈酸甘油酯、（4）β-谷甾醇-3-O-6-棕榈酰葡萄糖苷、（5）和尿嘧啶（6）.结论 化合物l ～6均为首次从该植物中分离得到.

Objective To study the chemical constituents of Alocasia macrorrhiza （ L. ） Schott. Methods Constituents were ex- tracted by 90% ethanol, isolated and purified by chromatographic techniques with silica gel, polyamide and so on. Their struc- tures were identified on the basis of physical - chemical properties and spectral data. Results Six compounds were isolated and i- dentified as 1,2 - dihydro - 6,8 - dimethoxy - 7 - hydroxy - 1 - （3,5 - dimethoxy - 4 - hydroxyphenyl） - N1, N2 - bis - [ 2 - （4 - hydroxyphenyl） ethyl] - 2,3 - naphthalene dicarboxamide （ 1 ）, cannabisin F （ 2 ）, palmitic acid （ 3 ）, 1 - monopalmitin （4）, sitosterol - 3 - O - 6 - palmityl - β - D - glucopyranoside （ 5 ）, and uracil （6）. Conclusion Compounds 1 - 6 were isola- ted from Alocasia macrorrhiza for the first time.