微波辐照下烯烃和重氮化合物无催化剂的环丙烷化反应

Catalyst-Free Cyclopropanation of Alkenes with Diazocompounds under Microwave Irradiation

在微波辐照下,重氮化合物和烯烃通过环丙烷化反应合成了环丙烷化合物.和传统需要金属催化剂的合成方法相比,该方法具有简便、对环境危害小等特点.同时,动力学研究结果表明微波辐照下的环丙烷化反应是二级反应.

Cyclopropane derivatives were prepared by the reaction of diazocompounds and alkene without catalyst under microwave irradiation, which demonstrated that it is an efficient method in organic chemistry. Compared with traditional metal catalyzed cyclopropane, this method is convenient and less harmful to environment. A second-order process was involved in the cyclopropanation as shown by the kinetic study.