VCI-C与MRI观察胎儿小脑蚓部、小脑幕形态的对比研究

Comparative Study of VCI-C and MRI in Morphology Observation of Fetal Vermis and Tentorium

目的探讨三维超声容积对比成像C平面(VCI-C)技术与MRI观察胎儿小脑蚓部、小脑幕形态方面是否具有一致性。方法应用VCI-C平面技术观察胎儿小脑蚓部形态正常与否,原裂、次裂显示情况,及测量脑干—小脑蚓部夹角(BVA)、脑干—小脑幕夹角(BTA),并与MRI图像进行比较。结果在显示小脑蚓部形态是否正常,原裂是否清楚方面,两种方法一致性高(Kappa值分别为0.91、0.78);在显示次裂方面,两种方法一致性好(Kappa=0.50);3种颅后窝畸形、BVA及BTA测量2种方法差异不具统计学意义(P均>0.05)。结论 VCI-C和MRI在观察胎儿小脑蚓部、小脑幕形态方面具有一致性,VCI-C平面技术可做为产前诊断与鉴别诊断胎儿颅后窝畸形的常规检查手段。

Objective To investigate whether the two imaging methods, including three-dimensional ultrasound volume contrast imaging C plane （VCI- C ） and MRI, axe identical in morphology observation of fetal vermis and tentorium. Methods VCI-C technology was applied to observe the fetal vermis shape, primary fissure and second fissure ; brainstem -vermis angle （ BV angle） and brainstem-tentorium angle （BT angle） were mea- sured, and the ultrasound results were compared with MRI results. Results In the display of vermis shape and primary fissure, the two methods showed a high concordance （ Kappa = 0.91,0.78 ） ; in the display of second fissure, the concordance of the two methods is also good （ Kappa =0.50 ） ; There was no statistical significance of the two methods in measuring BV angle and BT angle of three kinds of posterior fossa malformations （BV ： t =-0.343, -0.732,7.000 ; BT ： t =0.370,0.504, -0.600, all P〉 0.05 ） ; the two methods aretatistically identical in measuring BV, BT angle. Conclu- sion The two methods are identical in the morphology observation of fetal vermis and tentorium, VCI-C technology can be routinely applied for prena- tal diagnosis and differential diagnosis of fetal posterior fossa malformation.