新生儿缺氧缺血性脑病心肌酶谱测定的临床意义

The clinical Significance of Myocardiase Examination in Neonatal with HIE

目的：观察新生儿缺氧缺血性脑病 (HIE)心肌酶活性变化及心脏受损的情况。方法：采用连续监测法等方法检测了 110例新生儿 HIE与 45例正常新生儿脐血心肌酶谱测定值比较。结果：血清心肌酶谱 HIE新生儿组明显高于新生儿正常对照组(P<0 01)，而重度 HIE组显著高于轻、中度 HIE组 (P<0 01)。结论：新生儿 HIE做心肌酶谱测定是诊断其心肌损害、损害程度和估计预后的临床指标之一。有助于临床早期预测新生儿 HIE心肌损害及给予早期治疗。

Objective: To observe the change of neonatal myocardiase and the relationship between myocardiase and heart injury. Methods: Myocardiase in umbilical cord blood were measured by serial detections from 110 neonatal with HIE and 45 health neonatal. Results: Serum myocardiase level were higher signficantly in neonatal with HIE than that in the health neonatal (P<0.01). The serum myocardiase level were much higher in neonatal with severe HIE than that in neonatal with nild form of HIE. (P<0.01) Myocardiase examintion could be a clinical marker for early evaluating treating myocardial injury on HIE of neonatal.