龙胆泻肝汤联合西药治疗带状疱疹随机平行对照研究

Gentian Purging Liver Soup Combined Random Parallel Control Study Western Medicine Treatment of Herpes Zoster

[目的]观察龙胆泻肝汤联合西药治疗带状疱疹疗效。[方法]使用随机平行对照方法，将30例门诊患者按就诊顺序编号方法随机分为两组，治疗期间均禁食辛辣及油腻食物，戒烟、酒。对照组15例阿昔洛韦0．2g／次，1次／8h；三氮唑核苷（病毒唑）10mg／kg＋5％萄糖500mL静滴，1次／d；甲钴胺250～500ug，1次／d。伴水泡破裂2．5％龙胆紫溶液涂患处。治疗组15例龙胆泻肝汤（龙胆草10g，连翘、生地各15g，泽泻lOg，木通8g，车前子、黄芩、生栀仁、丹皮各10g，板蓝根、牛蒡子各15g，佩兰、甘草各lOg），水2000mL煎至500mL，3～4次／d，温服。疼痛重外用京墨涂抹。西药治疗同对照组。连续治疗7d为1疗程，治疗3个疗程。观测临床症状，皮疹、止疱、止痛、结痂、皮损痊愈时间，不良反应。治疗1疗程，判定疗效。[结果]治疗组痊愈12例，显效3例，总有效率100．00％。对照组痊愈6例，显效3例，无效6例，总有效率60．00％。治疗组疗效优于对照纽（P〈0．05）。止痛、止疱、结痂时间，总病程治疗纽均显著短于对照纽（P〈0．05）。[结论]龙胆泻肝汤联合西药治疗带状瑭．疮．疗效满意齐．副作用．佶彳导旌产．

[ Objective ] To observe the gentian purging liver soup combined western medicine treatment of herpes zoster. [ Methods ] Using random parallel control method, the method of 30 eases of clinic patients in clinic order number were randomly divided into two groups： treatment during fasting, spicy and greasy food, to give up smoking and wine. The control group of 15 eases of aeyelovir, 0.2 g/time 1 times/h; Three azole nitrogen nueleoside （ virazole ） 10 mg/kg ＋ 5% glucose 500 mL static drop, I/d, a eobah amine ug/250 ~ 500 times/d. With blisters rupture can be 2.5% gentian violet solution with hifu. Treatment group （ 15 eases gentian liver soup （ radix geutianae 10g, fruetus forsythiae and radix rehmanniae each 15g, alisma 10g, also 8g, plantain seed, radix seutellariae, each 10g Zhi kernel, cortex moutan, radix isatidis, frnetus aretii each 15 g, perrin, liquorice 10g ）, 2000 mL water decoction to 500 mL, 3 ~ 4 times/d, warm clothing, pain is the person that weigh for external use Beijing ink blot out. Western medicine treatment with the control group. Western medicine treatment with the control group. Continuous treatment 7 d is 1 treatment course, 3 period of treatment. Observation of clinical symptoms, prashes, adverse reactions. As a course treatment, judge curative effect. [ Result ] The treatment group 12 eases recovered, 3 eases had marked effect, total effective rate was 100.00%. Control group cure 6 eases, 3 eases were markedly effective, 6 no effect, the total effective rate was 60.00%. The treatment group curative effect is better than that of control group （ P〈0.05 ） . [ Conclusion ] Gentian purging liver soup combined western medicine in the treatment of herpes zoster and satisfactory curative effect, no side effect, is worth promoting.