天津市食品和公共场所从业人群HEV亚临床感染的流行趋势

An epidemic tendency analysis of HEV subclinical infection among employees in food industry and public places of Tianjin City

目的了解天津市食品和公共场所从业人群中戊型肝炎病毒(HEV)亚临床感染的流行趋势,旨在为戊型病毒性肝炎(戊肝)的预防和控制工作提供科学依据。方法对2010年3月—2012年12月期间在天津市疾病预防控制中心预防医学门诊部进行预防性健康检查者的资料进行统计分析,采用圆形分布法推算HEV亚临床感染的季节性特征。结果天津市食物和公共场所从业人群HEV亚临床感染存在一定的季节高峰(r=0.2270,P<0.01);此高峰平缓,高峰日为8月19日,高峰期为5月11日—11月28日。3年共检出HEV-IgM阳性者115人,HEV亚临床感染率为0.45%。食品行业从业人员HEV亚临床感染率明显高于公共场所,差异有统计学意义(χ2=6.511,P<0.05)。结论天津市食品和公共场所从业人群HEV亚临床感染具有一定的季节性特征,并与受检者行业类别具有较为明显的相关性。因此,今后防控工作的重点应放在5—11月,采取综合性措施加大对食品行业从业人员HEV感染的防控力度,有效控制传染源,保护广大市民的身体健康。

[ Objective] To understand the epidemic tendency analysis of Hepatitis E virus （HEV） subclinical infection among em- ployees in Tianjin City, and provide scientific evidence for hepatitis E control and prevention. [ Methods] Statistical analysis was performed on the results of the people who received health examination at preventive medicine clinic department in Tianjin CDC dur- ing Mar. 2010 to Dec. 2012, The seasonal characteristics of HEV subclinical infection were calculated by using circular distribu- tion method. [ Results] There were seasonal incidence peaks （r = 0. 227 0 ,P 〈 0.01） of HEV subclinical infection among employ- ees in Tianjin City. There was an easy curve and the peak date was Aug. 19th and the peak period werre from May. llth to Nov. 28th. A total of 115 employees were confirmed as the HEV-IgM positive, the rate of HEV subclinical infection was 0.45%. The employees in food industry had a higher rate than the public places, the deviation had a statistical significance（x^2 = 6. 511, P 〈 0. 05 ）. [ Conclusion] HEV subclinical infection has an epidemic tendency among employees in Tianjin, and has some relativity with the category of employments. Prevention and control work should be strictly strengthened from May to November, taking com- prehensive measures to keep food industry employees away from HEV infection, protecting the public health by controlling infectious source effectively.