摘要
在所有妇科肿瘤中,卵巢癌的治疗一直是临床工作面临的最艰巨的挑战。随着整体医疗技术的进步,卵巢癌的治疗手段也不断改进。传统的根治性手术联合辅助性化疗仍是其基本的治疗方法;而新辅助化疗及术前介入化疗为中晚期无法直接施行手术的患者争取了手术机会;腹腔热灌注化疗可安全有效地延缓复发、提高中晚期卵巢癌患者生存质量;靶向治疗、免疫治疗则是改善中晚期卵巢癌预后的主要趋势。本文旨在对中晚期卵巢癌的治疗现状做一综述,以期为提高中晚期卵巢癌患者的生存率和生存质量提供更多的参考依据。
Ovarian cancer had been the most difficult challenge in all gynecological tumors. Along with the ensemble medi- cal technology stepping forward, the treatment of ovarian cancer was continuously improved. Traditional radical operation and postoperative chemotherapy was still nonattribute-based approaches in ovarian cancer; neoadjuvant chemotherapy （NAC） and preoperative interventional chemoembolization strived for operation opportunity for advanced ovarian cancer patients who had lost operation opportunity; intraperitoneal hyperthermic chemotherapy＂ （IPHC） could safely and effectively postpone recidivation and improve the quality of life for advanced ovarian cancer patients; targeted therapy and immunotherapy were the major trend in prognosis for advanced ovarian cancer patients. This article was aimed to review the current situation of the therapies of middle- advanced ovarian cancer and provide references to enhance the survival rate and quality of life of middle-advanced ovarian can
出处
《肿瘤药学》
CAS
2013年第6期416-421,共6页
Anti-Tumor Pharmacy
基金
国家自然科学基金项目资助(No.81172375)
关键词
中晚期卵巢癌
根治性手术
新辅助化疗
腹腔热灌注化疗
靶向治疗
免疫治疗
Advanced ovarian cancer
Radical operation
Neoadjuvant chemotherapy
Preoperative interventional chem-oembolization
Intraperitoneal hyperthennic chemotherapy
Targeted therapy
Immunotherapy
