消炎止咳贴提取工艺的正交试验研究

Study of Orthogonal Test on Extraction Technology of Xiaoyan Zhike Plaster

目的 :优选消炎止咳贴的提取工艺。方法 :以麻黄碱和黄芩甙的含量为考察指标 ,对提取工艺进行L9(34 )试验。结果 :影响提取效率的因素大小顺序是 :A >D >C >B (A :乙醇浓度 ;B :乙醇用量 ;C :提取时间 ;D :提取次数 )。结论 :用 3倍量的 80 %的乙醇提取 3次 ,每次提取 2小时 ,为比较理想的提取工艺 ,其浸膏得膏率和有效成分的提取率均较高。

To choose the optimal extraction technology of Xiaoyan zhike plaster.Methods:The extraction technology was examined by L 9(3) 4 test and taking the content of Ephedrine and Baicalin as the inspection index.Results:The factors influencing the extraction efficiency in order were as follows:A>D>C>B(A:The density of ethanol,B:The amount of ethanol utilized,C:The refluxing and extracting time,D:The times of refluxing and extracting).Conclusion:The optimal extraction process obtained was that refluxing and extracting with the 3 fold of 80% ethanol for 3 times,2 hours for each time,the rates of both obtaining the extracts and the effective components were fairly high.