2012年大理州8县(市)健康人群麻疹IgG抗体水平监测分析

Monitoring analysis on measles IgG antibody level of healthy population in 8 counties of Dali Bai Autonomous prefecture in 2012

目的了解大理州健康人群中麻疹抗体水平，为制订消除麻疹策略提供科学依据。方法采用酶联免疫吸附试验（enzyme—linked immunosorbent assay，ELISA）对〈1岁、1～岁、3～岁、5～岁、7～岁、11～岁、15～岁、1〉20岁8个年龄组共计3066份末梢血检测麻疹IgG抗体。结果根据性别、年龄、县（市）、有无接种史分组进行卡方检验，其中性别没有统计学意义（P=0．148），在年龄、县（市）、有无接种史均有统计学意义（P〈0．05）。结论及时掌握人群的免疫水平，进一步提高麻疹疫苗的常规接种率和加强大年龄组人群麻疹疫情的监测是消除麻疹关键所在。

Objective To learn about the measles IgG antibody level in the healthy people of Dali Bai autono- mous prefecture, so as to provide the scientific basis for formulating strategy to eliminate measles. Methods Using enzyme - linked immunosorbent assay （ELISA） to test measles IgG antibodies in 3 066 peripheral blood specimens which came from 〈 1 years old, 1 -years old, 3 ~ years old, 5 -years old, 7 -years old, 11 - years old, 15 - years old, and ≥ 20 years old of total 8 groups. Results The datum was analyzed by chi - square test according to gender, age, county （city） , and presence of inoculation history group. There was no statistical significant difference in gender （P = 0. 148 ） . There were statistical significant differences （P 〈 0. 05 ） in age, county （city） , presence of inoculation history groups. Conclusions It is the key to eliminate the measles that we should grasp the crowd level of immunity, further improve the inoculation rate of measles vaccine and strengthen the monitoring of senior age group.