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新型糖尿病治疗药物GLP-1类似物的研发情况 被引量:1

Research progress and marketing of GLP-1 analogues antidiabetic medicine
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摘要 GLP-1类似物具有独特的药理学特性,降糖作用呈现"血糖浓度依赖性",最接近内分泌降糖生理状态,不会引起显著地临床低血糖反应,还可以提高胰岛素的敏感性,改善胰岛β细胞功能,此外,还可可控制热量摄入,增强饱腹感而降低食欲。GLP-1类似物已成为降血糖领域研究的热点。本文就目前已上市及处于研发晚期的GLP-1类似物进行综述。
作者 魏臻
机构地区 江苏省药学会
出处 《药品评价》 CAS 2013年第23期42-46,共5页 Drug Evaluation
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