尿毒症患者尿红细胞形态变化及其影响因素的探讨

Urinary Erythrocytes Morphology and its Influential Factors in Patients with Uremia

目的 探讨尿毒症患者尿红细胞形态变化及其影响因素。方法应用染色法按 Ｆａｉｒｌｅｙ尿红细胞形态分类和Ｃｈｕ尿红细胞形态新的分类计数法，观察３５倒尿毒症患者尿红细胞形态变化。结果两种方法均证明，尿毒症患者尿红细胞正常形态明显增多，大于７０％。结论 尿毒症患者尿红细胞形态大部分为正常，其机制与肾小球毛细血管基底膜裂孔增大，红细胞完整漏出和肾小管不能形成渗透梯度有关。

Objective To investigate the changes of urinary erythrocytes shape and its influential factors in patients with uremia. Methods in 35 patients with uremia, the shape of urinary erythrocytes was observed by staining, and classified by Fairley and Chu renal erythrocytes counting. Results The rate of normal shape erythrocytes was more than 70%. Conclusion In patietns with uremia, the urinary erythrocytes shape are mostly normal. It may be related to the hiatus of glomerular basement membrane (GBM) and interstitial pathogenic changes of renal tubular.