摘要
目的 通过对外周血CA19-9、CEA的联合检测,了解其对消化道恶性肿瘤的诊断价值及临床意义.方法采用酶联免疫吸附法对128例消化道恶性肿瘤患者的CA19-9、CEA水平进行测定.结果 肿瘤组CA 19-9水平显著高于正常对照组(P<0.05),阳性率:结/直肠癌组16.66%,胃/贲门癌组13.28%.肿瘤组CEA水平显著高于正常对照组(P<O.001),阳性率:结/肠癌组52.38%,胃/贲门癌组38.64%.结论 CA 19-9和CEA的联合检测,可提高消化道肿瘤诊断的特异性,并对疗效观察、监测肿瘤的转移与复发有实际意义.
ve To evaluate the diagnostic value and the clinical significance for measuring the serumlevels of CA 19-9 and CEA in gastro-intestinal cancer.Methods The serum levels of CA 19-9 and CEA were deter-mined in 128 cases with gastro-intestinal cancer by enzyme immunometric assay. Results In cancer patients, theCA 19-9 levels were markedly elevated(P < 0. 05), the positive rate was 16. 66% in colorectal cancer and 13. 28% incarcinoma ventriculi and cardiac cancer. The CEA levels were markedly elevated (P < 0. 001) .The positive rate was52. 38% in colorectal cancer and 38. 64% in carcinoma ventriculi and cardiac cancer. Conclusion The examination ofCA 19-9 and CEA can elevate the specificity of diagnosis of gastrointestinal cancer, and have positive value for de-tecting the treatment effect and metastasis.
