摘要
Two new Cl-symmetric primary-secondary diamines were synthesized via the reaction of （S,S）-1,2- diphenyl ethylene diamine with 3,5-ditert-butyl salicylal- dehyde and salicylaldehyde, respectively, followed by reduction with NaBH4. The combination of the ligand from 3,5-ditert-butyl salicylaldehyde with CuBr could effciently catalyze the Henry reaction to afford β- nitroalkanols in moderate to good yields （up to 87%） and high enantioselectivities （up to 88% ee）. A possible mechanism of the reaction was proposed.
Two new Cl-symmetric primary-secondary diamines were synthesized via the reaction of （S,S）-1,2- diphenyl ethylene diamine with 3,5-ditert-butyl salicylal- dehyde and salicylaldehyde, respectively, followed by reduction with NaBH4. The combination of the ligand from 3,5-ditert-butyl salicylaldehyde with CuBr could effciently catalyze the Henry reaction to afford β- nitroalkanols in moderate to good yields （up to 87%） and high enantioselectivities （up to 88% ee）. A possible mechanism of the reaction was proposed.
