左氧氟沙星三联疗法与阿莫西林三联疗法治疗消化性溃疡的效果比较

Comparative analysis on clinical efficacy of levofloxacin triple therapy and amoxicillin triple therapy for the treatment of peptic ulcer

目的比较左氧氟沙星三联疗法和阿莫西林三联疗法治疗消化性溃疡的临床效果。方法选取本院收治的48例消化性溃疡患者,随机分为对照组和观察组,对照组给予阿莫西林三联疗法治疗,观察组给予左氧氟沙星三联疗法治疗。比较两组患者日均费用、治疗总有效率和并发症发生率。结果两组患者治疗总有效率和并发症发生率差异无统计学意义(P>0.05);观察组患者日均费用显著少于对照组。结论左氧氟沙星三联疗法和阿莫西林三联疗法治疗消化性溃疡均安全有效,左氧氟沙星三联疗法更经济实惠,值得推广使用。

Objective To investigate clinical efficacy of levofloxacin triple therapy and amoxicillin triple therapy in treatment of peptic ulcer. Methods 48 cases of peptic ulcer in our hospital were randomly divided into control group and observation group. Control group was given amoxicillin triple therapy. Observation group was given levofloxacin triple therapy. The daily cost, total effective rate and complication rate of two groups were compared. Results The total effective rate and complication rate of two groups were not significantly different （P〉0.05）.Daily cost of observation group was significantly lower than control group.Conclusion Both levofloxacin triple therapy and amoxicillin triple ther- apy for the treatment of peptic ulcer are effective and safe. The levofloxacin triple therapy is easily widely used for lower fee.