缺血预适应对糖尿病患者急性心肌梗死并发症的影响

Effects of ischemic preconditioning on complications of acute myocardial infarction in diabetics

目的观察缺血预适应(IP)对糖尿病患者急性心肌梗死(AMI)并发症的影响。方法 AMI患者172例,分为4组:无糖尿病IP组(A组)、无糖尿病无缺血预适应(NIP)组(B组)、糖尿病IP组(C组)、糖尿病NIP组(D组),其中糖尿病患者52例,分别比较AMI并发症发生率。结果 A组AMI并发症发生率明显低于B组(P<0.05),心功能指标优于B组(P<0.01),C、D两组间比较各项指标无显著差异(P>0.05)。结论 IP对于无糖尿病的AMI患者有心脏保护作用,降低并发症发生率,而在糖尿病患者中上述作用不明显。

Objective To observe the effect of ischemic preconditioning （IP） in diabetic patients with acute myocardial infaretion（AMI） complications affected. Methods A total of 172 patients divided into four groups： non-diabetic IP group （A group）, non-diabetic NIP group （B group）, diabetes IP group （C group）, diabetes NIP group （D group）, in which 52 patients with diabetes cases, compared with the AMI complication rate of each group. Results A group of AMI compli- cation rate was significantly lower than in group B （P 〈0.05）, heart function indexes were significantly better than group B （P 〈0.01）, the indicators between the two groups of C, D had no significant difference （P 〉0.05）. Conclusion IP for AMI patients without diabetes have heart protective effect, reducing the incidence of complications, and these ef- fects in diabetic patients is not obvious.