临床药师对肛瘘切除术抗菌药物使用干预研究

Study on clinical pharmacists intervening to prophylactic use of antimicrobial drug of anal fistula resection

目的:评价临床药师干预肛肠科肛瘘切除术抗菌药物应用的效果。方法:分别抽取干预前(2011年8月)、干预后(2012年8月)医院肛肠科肛瘘切除术患者病历各53份,对抗菌药物的合理性进行对比分析。结果:经临床药师干预,肛瘘切除术患者抗菌药物使用合理性明显改善,抗菌药物品种由干预前的头霉素和氟喹诺酮类调整为二代头孢菌素和林可霉素类,术前0.5～2小时用药者由干预前15.09%提高至83.02%,术后用药天数由干预前的9.11天降至4.79天,抗菌药物费用由1225.91元降至629.60元。结论:临床药师对肛瘘切除术使用抗菌药物的干预是可行和有效的,干预对Ⅲ类切口用药的合理、有效、安全、经济起到积极的作用。

Objective： To evaluate the clinical pharmacist intervention anorectal branch anal fistula resection surgery antimicrobial agents application of the effect.Methods： Was extracted before the intervention（ August 2011）,after the intervention（ August 2012） Hospital Anorectal Branch anal fistula in patients undergoing medical records of the 53,the comparative analysis of antimicrobial reasonable.Results： After clinical pharmacist intervention,anal fistula in patients undergoing antimicrobial drug use reasonable significantly improved antimicrobial agents varieties of by the cephamycin before the intervention and the fluoroquinolones adjusted to the second-generation cephalosporins and lincomycin,preoperative 0.5～2-hour drug users increased by 15.09% before intervention to 83.02%,the number of days of postoperative medication dropped to 4.49 days from 9.11 days before the intervention,antimicrobial drug costs by 1225.91 yuan to 629.60 yuan.Conclusion： The clinical pharmacist anal fistula resection of the use of antimicrobial drugs intervention is feasible and effective,intervention the class Ⅲ incision medication reasonable,effective,safe,economical and play a positive role.