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爱必妥联合伊立替康治疗肠癌的护理 被引量:2

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摘要 爱必妥,即西妥昔单抗,属于人鼠嵌合性IgG单克隆抗体,通过与表皮生长因子受体的特异性结合,抑制癌细胞的增值及受体磷酸化,阻断下行信号通道;盐酸伊立替康是喜树碱的半合成衍生物,是拓扑异构酶I的特异性抑制剂,引起DNA单链断裂,阻碍DNA复制与合成。最终抑制细胞分裂。2012年3月至2013年3月我科应用爱必妥联合盐酸伊立替康治疗肠癌8例,通过减少并发症的发生及出现的毒副反应进行有针对性的护理,保证治疗顺利进行。
作者 陈兰
出处 《齐齐哈尔医学院学报》 2013年第22期3383-3383,共1页 Journal of Qiqihar Medical University
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