生长抑素联合奥美拉唑治疗重度老年上消化道出血的临床疗效

Clinical efficacy of somatostatin plus omeprazole on elderly patients with severe upper gastrointestinal bleeding

目的观察生长抑素联合奥美拉唑治疗重度老年上消化道出血的临床疗效。方法选取2008年3月至2013年4月在安徽省萧县人民医院消化内科住院治疗的部分重度老年上消化道出血患者共40例,按随机数字表法分为两组,奥美拉唑组20例,奥美拉唑+生长抑素组20例。两组患者的一般临床资料比较差异无统计学意义(P>0.05)。结果两组患者入院治疗72 h后,奥美拉唑+生长抑素组收缩压、脉搏、血红蛋白恢复情况较奥美拉唑组明显好转,差异有统计学意义(P<0.05)。结论生长抑素联合奥美拉唑钠治疗重度老年上消化道出血具有止血迅速、失血量少等优点,值得临床推广。

Objective To observe the clinical efficacy of somatostatin plus omeprazole on elderly patients with severe upper gastrointestinal bleeding. Methods From March 2008 to April 2013, 40 patients with severe upper gastrointestinal bleeding in Xiaoxian people＇ s hospital were choosed, and they were randomly divided into two groups： omeprazole group （20 cases） and omeprazole ＋ somatostatin group （20 cases）, There were no significant difference in the general clinical data between the two groups （P 〉 0. 05）. Results Seventy-two hours after admission, in term of systolic blood pressure, pulse rate, hemoglobin recovery, omeprazole plus somatostatin group improved more significantly than omeprazole group, the differences were significant （P 〈 0. 05）. Conclusion Somatostatin plus omeprazole sodium in the treatment of severe upper gastrointestinal bleeding has the advantages of rapid hemostasis, less blood loss, so is worthy of promotion.