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罗红霉素对Parkinson’s病患者卡麦角林药物动力学的影响

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摘要 目的观察罗红霉素对Parkinson’s病(PD)患者卡麦角林药物动力学的影响。方法 15例PD患者接受稳定剂量的卡麦角林治疗,给予口服克林霉素(300 mg/d,连用6 d)治疗前测定卡麦角林血药浓度,停止应用罗红霉素14 d后再次检测。结果 PD患者使用克拉霉素后血浆卡麦角林浓度增加2.21倍。结论合用罗红霉素可增加PD患者卡麦角林的药物浓度。
作者 卞德轩
出处 《临床医学》 CAS 2013年第11期112-113,共2页 Clinical Medicine
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参考文献6

  • 1冯涛,芦林龙,李伟,王拥军.血管性帕金森综合征的多巴反应性研究[J].中华老年心脑血管病杂志,2007,9(1):42-44. 被引量:10
  • 2方思伟.卡麦角林治疗帕金森病的临床研究[J].中华神经医学杂志,2005,4(4):387-388. 被引量:1
  • 3Del Dotto P,Bonuccelli U. Clinical pharmacokinetics of cabergoline[J].{H}Clinical Pharmacokinetics,2003.633-645.
  • 4Westphal JF. Macrolide-induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4:an update focused on clarithromycin,azithromycin and dirithromycin[J].{H}British Journal of Clinical Pharmacology(England),2000.285-295.
  • 5Ausband SC,Goodman PE. An unusual case of clarithromycin associated ergotism[J].{H}JOURNAL OF EMERGENCY MEDICINE,2001.411-413.
  • 6Christensen J,Dupont E,Ostergaard K. Cabergoline plasma concentration is increased during concomitant treatment with itraconazole[J].{H}Movement Disorders,2002.1360-1362.

二级参考文献17

  • 1贾晓晶,龚守良,刘树铮,Rausch Wolf-Dieter.帕金森病多巴胺能神经元模型的建立(英文)[J].中华神经医学杂志,2004,3(5):382-386. 被引量:3
  • 2王新德.帕金森病和帕金森综合征的诊断标准和鉴别诊断[J].中华神经精神科杂志,1985,18(4):256-256.
  • 3Rinne UK,Bracco F,Chouza C,et al. Cabergoline in the treatment of early Parkinson' s disease: results of the first year of treatment in a double-blind comparison of cabergoline and levodopa[J]. Neurology,1997,48(2): 363-368.
  • 4Belanger N,Gregoire L,Tahar AH,et al. Chronic treatment with small doses of cabergoline prevents dopa-induced dyskinesias in parkinsonian monkeys[J]. Mov Disord,2003,18(12): 1436-1441.
  • 5Pastor P,Tolosa E. Cabergoline in the treatment of Parkinson's disease[J]. Neurologia,2003,18(4): 202-209.
  • 6Barone P. Clinical strategies to prevent and delay motor complications [J]. Neurology,2003,6 (Suppl 3): S12-16.
  • 7Inzelberg R,Schechtman E,Nisipeanu P. Cabergoline,pramipexole and ropinirole used as monotherapy in early Parkinson ' s disease: an evidence-based comparison[J]. Drugs Aging,2003,20(11): 847-855.
  • 8Smala AM,Spottke EA,Machat O,et al. Cabergoline versus levodopa monotherapy: a decision analysis[J]. Mov Disord,2003,18(8): 898-905.
  • 9.Rabey JM,Nissipeanu P,Inzelberg R,et al. Beneficial effect of cabergoline,new long-lasting D2 agonist in the treatment of Parkinson' s disease[J]. Clin Neuropharmacol,1994,17(3): 286-293.
  • 10Bhomraj T, Nelson L, Robinson T. Vascular parkinsonism-an important cause of parkinsonism in older people[ J]. Age and Ageing, 2005, 34: 114-119.

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