偶然分支杆菌爆发皮肤感染59例临床观察

Clinical observation of 59 cases with outbreak dermatic infection caused by M.fortuitum

目的 观察偶然分支杆菌爆发皮肤感染的特点、诊断、治疗及转归。方法 对 1999年 1月～ 12月间住院治疗并经细菌、病理、B超证实为偶然分支杆菌皮肤感染者 59例的临床特点、诊疗观察结果等作统计分析。结果 本组患者平均年龄 32 .3岁 ,男∶女为 1∶5.6 ,平均发病时间为 55± 30 .5天。 59例计有感染灶 76处 ,臀部占 92 .2 %。经细菌学证实 39例 ,占 6 6 .1% ,阴性 2 0例中有 12例经病理证实 ,二者计 51例 ,占 86 .4 %。所有患者均采用敏感抗生素 +有协同作用的抗结核药化疗 ,适应症病例施以外科处理。全部患者均临床治愈出院 ,随访 12个月未见复发病例。结论 本次感染为偶然分支杆菌所致 ,虽获治愈效果 。

Objective To study the characteristics of the dermatic outbreak infection caused by M.fortuitum.Methods Analyzing the clinical characteristics and therapeutic outcome of 59 cases with dermatic infection of M.fortuitum,who were admitted from January to December 1999 and confirmed by bacteriology,pathology and ultrasonic B.Results The average age of 59 cases is 32.3 years old,the ratio of male to female is 1∶5.6;and average length of illness is 55±30.5 days.The 59 cases have 76 lesions92.2% of the lesions are located in the buttocks.39 case are confirmed by bacteriology accounting for 66.1% and 12 cases out of the 20 negative cases checked by bacteriology are later found positive by pathology.The total 51 positive cases account for 86.4%.All the cases are treated with the antibiotics which the bacteria are sensitive to and the antituberculotic chemotherapy which can generate cooperative effect.The cases indicated of surgery will be treated accordingly.All the cases are discharged cured.The six month follow up has seen no relapse.Conclusion The infection is caused by M.fortuitum.The therapeutic outcome is satisfactory.