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2型糖尿患者的胰岛素抵抗与脂代谢紊乱 被引量:1

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摘要 目的 研究 2型糖尿病患者胰岛素抵抗与血脂变化特点。方法 对 68例 2型糖尿病患者及 5 0例正常人血脂、血糖及胰岛素水平进行测定 ,观察 2型糖尿病患者上述指标变化特点。结果  2型糖尿病患者与正常对照组相比有较高的总胆固醇 [(5 68± 0 67)mmol/Lvs (4 10± 0 61)mmol/L ,P <0 0 1]、甘油三酯 [(1 75± 0 0 7)mmol/Lvs (1 40± 0 0 5 )mmol/L ,P <0 0 1]、LDL -C[(3 40± 0 5 5 )mmol/Lvs (2 3 1± 0 5 1)mmol/L ,P <0 0 1]及apoB[(1 96± 0 5 0 )g/Lvs(1 61± 0 14 )g/L ,P <0 0 5 ] ,较低的HDL -C[(1 2 1± 0 3 4 )mmol/Lvs(1 78± 0 3 6)mmol/L ,P <0 0 1]及apoA[(1 40±0 2 1)g/Lvs(1 84± 0 3 6)g/LP <0 0 1] ,且胰岛素敏感性 [(4 46± 0 45 )vs(3 86± 0 42 ) ]也是降低的。结论  2型糖尿病不仅存在脂代谢紊乱 。
出处 《广东医学》 CAS CSCD 2001年第2期147-148,共2页 Guangdong Medical Journal
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