急性冠脉综合征早期管理及抗凝药物选择

Early management and choice of anticoagulants for acute coronary syndrome

急性冠脉综合征是临床常见的危急重症。随着对急性冠脉综合征病理生理认识的深入,发现易损斑块的破裂、继发血栓形成是急性冠脉综合征发病的重要机制。早期再灌注和抗凝治疗是急性冠脉综合征治疗的两个重要策略。近年来,这两方面的临床研究和循证医学证据越来越丰富,相关指南也推陈出新。

Acute coronary syndrome （ACS） is an emergent and intensive care disease commonly encountered in clinical practice. With the further study on the pathophysiology of ACS, it is found that rupture of vulnerable plaque is the core mechanism of ACS. Early reperfusion and anticoagulation treatment are two important strategies dealing with ACS. In recent years, abundant clinical studies and evidence-based medicine practice make efforts to this two fields, making the related guidelines updated. In this paper we review the advance in reperfusion and anticoagulation treatment in ACS.