南京地区无偿献血者RH阴性血液复检不合格情况分析

Analysis of retesting results and disqualification situation of blood screening for RH-D negative individuals in voluntary blood donors in Nanjing

目的:分析南京地区无偿献血者中RH阴性血的检出结果和复检不合格情况,寻求减少稀有血型血液浪费的对策。方法:对2006-2011年间南京地区无偿献血者的血液标本进行检测,并对结果进行统计分析。结果:近年来RH阴性血比例有逐年下降的趋势,2011年有所回升。同时,其复检不合格率却呈现出逐年上升的趋势,由2006年的0.28%上升至2011年的1.92%。其中以HBsAg和ALT不合格为主要报废原因。在不合格人群中,报废血量为200ml的人数逐年上升,但总体仍以捐献300ml、400ml为主,其中非固定与固定献血者比例为19∶7。不合格群体分布以来自南京郊县的青壮年已婚男性为主,但近年来呈现出高学历以及南京地区外来人群报废情况增加的趋势。结论:减少RH阴性血液报废,不仅需要提高检测试剂质量,规范人员操作;同时需要加强宣传招募工作,尤其加强对于重复献血者的招募,及时招募暂时淘汰成员归队,促进稀有血型献血工作的可持续发展。

Objective：To analyze retesting results and disqualification situation of the blood screening for RH D-individuals in voluntary blood donors in Nanjing,and explore the strategy to reduce waste of these rare blood re- sources. Method：The samples of voluntary blood donors in Nanjing from 2006- 201t were retested after initial rapid detection and the results were analyzed. Result： The D-blood proportion was decreasing year by year despite a rally in 2011 ,while the unqualified rate of the D-blood products was gradually increasing in recent years, which from 0.28% （in 2006） to 1. 92% （in 2011）. The main cause of disqualification was HBsAg and ALT. Among the unqualified group,the number of 200 ml blood donators was rising, with the unvariably dominating role of the 300 ml and 400 ml blood donators. Meanwhile,the ratio of the unfixed blood donors to the fixed ones was 19 to 7. The unqualified group distribution was mainly composed of married male young adults, most of whom were from the suburb of Nanjing. However,well educated population and external population tended to grow in number. Conclu- sion：Not only improving the quality of detection reagent and standardizing operative technique would be helpful to reduce waste of D-blood products, but also strengthening propaganda and recruitment work would be significant to promote sustainable development for rare blood donation cause, especially strengthening the recruitment of repeat donors and the donors who might return after temporary deferral.