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核素^(131)I治疗分化型甲状腺癌辐射并发症的防治 被引量:5

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摘要 目的探讨碘-131(131I)治疗分化型甲状腺癌(DTC)辐射并发症的预防与处置方法。方法选择经手术后病理确诊并完成131I治疗的DTC患者100例,其中男22例,女78例,年龄9~75岁。在131I治疗实施期间先采取预防措施;对发生的并发症进行诊断处理,对照疗效,建立辐射并发症的解决方案。结果 100例患者的298次131I治疗中发生各种辐射并发症199例次,占全部治疗次数的68.9%(199/289)。其中局部辐射反应最常见,共发生141例次,占全部并发症的70.9%(141/199),而大部分(100/141)发生于第一次治疗中;放射性胃炎发生31例次,占15.6%(31/199);涎腺炎发生22例次,占11.1%(22/199);骨髓一过性抑制发生4例次,占2.0%(4/199);放射性皮炎发生1例,占0.5%(1/199),此例患者疼痛剧烈。以上辐射并发症经处理后均痊愈。其他并发症在本组病例中未发生。预防与准备均在治疗前、中实施。结论 131I治疗DTC确有辐射并发症发生,多数症状轻微,对症处理后能够很快缓解痊愈。严重并发症发生的几率小,但起病重,预防是关键。如有发生,则应及时诊治,不使其发生严重后果。
机构地区 解放军第
出处 《中国辐射卫生》 2013年第6期762-764,共3页 Chinese Journal of Radiological Health
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参考文献7

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