育龄妇女27334例的弓形虫近期感染状况回顾性分析

Retrospective analysis of Toxoplasma gondii recent infection in 27 334 women of childbearing age

目的回顾性分析育龄妇女弓形虫（TOX）近期感染状况，为预防和治疗TOX感染提供参考依据。方法采用酶联免疫吸附试验（ELISA）方法，对2009—01～2012—12期间来我院就诊的育龄妇女血清TOX—IgM浓度进行检测，并对检测结果进行回顾性分析，按年份和年龄进行分组。结果不同年份的TOX—IgM抗体阳性率差异有统计学意义（X2=12．26，P〈0．05），阳性率有逐年显著上升的趋势。不同年龄阶段各组TOX—IgM抗体阳性率差异无统计学意义（X2=3．00，P〉o．05）。结论育龄妇女TOX近期感染有逐年上升的趋势，应对育龄妇女加强TOX防治知识的宣传，提高出生人口素质。

Objective To investigate the recent infection status of Toxoplasma gondii （TOX） among women of childbearing age, and to provide references in prevention and treatment of TOX infection. Methods Using enzyme-linked immunosorbent assay （ELISA） ,the serum levels of TOX-IgM in women of childbearing age were determined from January 2009 to December 2012. Then the data were statistically analyzed. Results The positive rate of TOX-IgM antibody was significantly different in different years （X2 = 12. 26,P 〈 0.05 ）, and the positive rate of TOX-IgM antibody showed an ascending trend year by year. No significant difference in the positive rate of TOX-lgM antibody was found among different age groups （X2 = 3. O0,P 〉 O. 05 ）. Conclusion The recent infective rate of TOX in women of childbearing age shows an ascending trend, and the publicity of TOX prevention and treatment knowledge should be strengthened to improve the diathesis of newborns.