650例支气管哮喘患者的支气管舒张和激发试验结果分析

Analysis of bronchial dilation test and bronchial provocation test for 650 cases of asthma patients

目的分析支气管哮喘患者的气道可逆性和变异性水平。方法 650例临床诊断为支气管哮喘的患者,527例进行支气管舒张试验,123例进行支气管激发试验,对其阳性率及合并气流受限的情况进行分析。结果支气管舒张试验阳性率为41.4%,支气管激发试验阳性率为52.0%。650例患者中,气流受限(FEV1/FVC%<70%)的比例达34.0%,其中支气管舒张试验中合并气流受限的193例患者中,阳性率为61.7%。结论支气管舒张试验敏感性不高,需要反复测定,激发试验的阳性率不高,阴性患者不能排除哮喘诊断。合并气流受限的支气管哮喘患者,舒张试验阳性比例高,提示这部分患者的病情可能处于急性发作期,需要积极治疗。

Objective To analyse the airway reversibility and variability for bronchial asthmatic patients .Methods The status of test positive ratio and combined airflow limitation were analysis for 650 Clinical diagnosed asthmatic patients .527 cases were given bronchial dilation test and 123 cases were given provocative test .Results Positive ratio of 527 cases bronchial dilation test was 41 . 4% .Positive ratio of 123 cases provocative test was 52 .0% .The airflow limitation（FEV1/FVC% 〈70% ） ratio of total 650 cases was 34 .0% .In the 193 cases of combined airflow limitation patients which was given bronchial dilation test ,the positive ratio of bronchial dilation test was 61 .7% .Conclusion Bronchial dilation test need repeat because of its less sensitivity .The positive ratio of provocative test is not high ,so the patients of provocative test negative couldn′t exclude the diagnosis of asthma .The ratio of bronchial dilation test was high for combined airflow limitation asthmatic patients .Its may clew that the patients combined airflow limitation may be exacerbation and need actively therapy .