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骨质疏松病人应用唑来膦酸钠的观察与护理 被引量：5

Observation and nursing of application of zoledronic acid sodium for osteoporosis patients
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摘要 骨质疏松（osteoprosis,OP）[1]是一种以骨量减少、骨组织结构破坏、骨脆性增加和易于骨折为特征的代谢性疾病.随着人口老龄化的发展,骨质疏松症已成为危害人类健康的常见病、多发病,给家庭及社会增添了沉重的负担[2].目前,治疗骨质疏松的药物较多,如降钙素、双膦酸盐和雌激素等.这些药物具有较好的疗效,但由于骨质疏松症病人需坚持长期治疗[3],药物依从性不佳,导致治疗效果欠佳.2000年美国食品药物管理局（U.SFood and Drug Administration,FDA）批准第三代双膦酸类药物——唑来膦酸钠（密固达）用于治疗骨质疏松,每年静脉注射1次,注射3次后可以获得比较满意的疗效.
作者 颜叶超 陈亚梅 王西英 沈新艳
机构地区 上海市第十人民医院
出处 《护理研究（中旬版）》 2013年第12期4065-4067,共3页 Chinese Nursing Researsh
关键词 骨质疏松 唑来膦酸钠 护理
分类号 R473.5 [医药卫生—护理学]
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参考文献9

二级参考文献32

  • 1杨玲,殷晓进.锶与骨矿代谢[J].中国骨质疏松杂志,2004,10(3):384-387. 被引量：17
  • 2彭六保,崔巍.唑来膦酸的临床应用研究进展[J].中国新药与临床杂志,2007,26(3):237-240. 被引量：36
  • 3Cramer JA,Amonkar MM,Hebbom A,et al.Compliance and persistence with bisphosphonate dosing regimens among women with postmenopausal osteoporosis[J].Curt Med Res Opin,2005,21(12):1453-1460.
  • 4Lo JC,Pressman AR,Omar MA,et al.Persistence with weekly alendronate therapy among postmenopausal women[J].Osteoperos Int,2006,17(6):922-928.
  • 5Huybrechts KF,lshak KJ,Caro JJ.Assessment of compliance with osteoperosis treatment and its consequences in a managed care population[J].Bone,2006(6),38:922-928.
  • 6Siris ES,Harris ST,Rosen CJ,et al.Adherence to bisphosphonate therapy and fracture rates in osteoporotic women:relationship to vertebral and nonvertebral fractures from 2 US claims databases[J].Mayo Clin Proc,2006.81(8):1013-1022.
  • 7Siris ES,Silverman S,Abbott T,et al.Adherence to bisphosphonates (BPs) is associated with reduced fr acture risk in women with posunenopausal osteoperosis (PMO)[J].Menopanse,2005,12:75.
  • 8Black DM,Delmas PD,Eastell R,et al.Once-yearly zoledronic acid for treatment of postmenopansal osteoporosis[J].N Engl J Med,2007,356(18):1809-1822.
  • 9Lyles KW,Coion-Emetic CS,Magaziner JS,et al.Zoledronic acid and clinical fractures and mortality after hip fracture[J].N Engl J Med,2007,357(18):1799-1809.
  • 10中华医学会编.临床诊疗指南《骨质疏松症和骨矿盐疾病分册》[M].北京:人民卫生出版社,2006:2-3.

共引文献109

同被引文献34

  • 1中国健康促进基金会骨质疏松防治中国白皮书编委会.骨质疏松症中国白皮书.中华健康管理学杂志,2009,3(3):148-156.
  • 2Dempster DW. Osteoporosis and the burden of osteoporosis-related fractures[J]. Am J Manag Care, 2011, 17(6 suppl) :S164-S169.
  • 3Piirtola M, Vahlberg T, LppSnen M, et al. Fractures as predictors of excess mortality in the aged--a population-based study with a 12 -year follow-up [J]. Eur J Epidemiol, 2008,23 ( 11 ) : 747 -755.
  • 4Pike C, Bimbaum HG, Schiller M, et al. Economic burden of privately insured non-vertebral fracture patients with osteoporosis over a 2-year period in the US[J]. Osteoporos Iut, 2011,22( 1 ) : 47 -56.
  • 5Werner P. Knowledge about osteoporosis: assessment, correlates and outcomes [J]. Osteoporos Int, 2005,16 ( 2 ) : 115-127.
  • 6Pike CT, Bimbaum HG, Schiller M, et al. Prevalence and costs of osteoporotic patients with subsequent non- vertebral fractures in the US[J]. Osteoporos Int, 2011,22(10) :2611-2621.
  • 7International Osteoporosis Foundation. Three steps to unbreakable bones[EB/OL]. [2011-10-13]. http ://www. ioibonehealth, org/ three-steps-unbreakable-bones-0.
  • 8Yeap SS, Goh EM, Das Gupta E. Knowledge about osteoporosis in a Malaysian population[J]. Asia Pac J Public Health, 2010, 22 (2) : 233-241.
  • 9Saw SM, Hong CY, Lee J, et al. Awareness and health beliefs of women towards osteoporosis [J]. Osteoporos Int, 2003, 14 ( 7 ) : 595-601.
  • 10Gemalmaz A, Oge A. Knowledge and awareness about osteoporosis and its related factors among rural Turkish women [J]. Clin Rheumatol, 2008, 27(6):723-728.

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护理研究（中旬版）
2013年 第12期

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