正常成年人眼眶脂肪体积随年龄变化的磁共振成像定量分析

Quantitative analysis of orbital fat volume changes with age in normal adults using magneticresonance imaging

目的利用磁共振成像（MRI）研究不同年龄段正常成年人眼眶脂肪体积的变化，探讨正常成年人眼眶脂肪体积随年龄变化的趋势。方法调查研究。召集我院144例（男女各半，288眼）成人健康体检志愿者，按年龄分组（1组，18～35岁；2组，36～50岁；3组，≥51岁）平均入组不同年龄组男、女各为24例，行眼眶MHI扫描并测量眼眶脂肪体积，经标准化处理后，分析不同性别及年龄段正常成年人眼眶脂肪体积变化。采用单因素方差分析、独立样本t检验、Spearman等级相关进行数据分析。结果男性各年龄组之间眶脂肪体积差异无统计学意义（F=0．787，P〉0．05），女性各年龄组之间眶脂肪体积差异无统计学意义（F=1．183，P〉0．05），男、女2组眼眶脂肪体积比较差异无统计学意义（t=1．029，P〉0．05），眼眶脂肪体体积与年龄之间无相关性（r=-0．087，P〉0．05）。结论正常成年人眼眶脂肪体积随年龄增长无明显变化，男、女性别之间无明显差异。

Objective To explore the trends in orbital fat volume in different age groups using magnetic resonance imaging （MRI）. Methods Investigative study. One hundred forty-four normal adults （18-72 year olds, 288 eyes） were divided into six groups according to age and sex： 18-35 years old, 36-50 years old, ≥51 years old with 24 cases in every group. The orbital fat volumes in all the above groups were examined by MRI scans and the measured data were standardized. ANOVA was used to analyze the changes in orbital fat volume in the different gender and age groups. Independent t test and Spearman correlation was also used. Results The orbital fat volume showed no significant differences among the three different male age groups （F=0.787, P〉0.05） and female groups （F=1.183, P〉0.05）. In addition, there was no significant difference in the orbital fat volume between the male and female groups （t=1.029, P〉0.05）. There was no correlation between orbital fat volume and age （r=-0.087, P〉0.05）. Conclusion There were no significant changes in orbital fat volume with increasing age and there were no differences in orbital fat volume between normal adult male and female groups.