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Voltammetric quantitation of nitazoxanide by glassy carbon electrode

Voltammetric quantitation of nitazoxanide by glassy carbon electrode
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摘要 The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson (B-R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20-140 ~tg/mL. The limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 5.23 la~/mL and 17.45 la~/mL, respectively. The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson (B-R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20-140 ~tg/mL. The limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 5.23 la~/mL and 17.45 la~/mL, respectively.
出处 《Journal of Pharmaceutical Analysis》 SCIE CAS 2013年第6期452-455,共4页 药物分析学报(英文版)
关键词 NITAZOXANIDE Squarewave voltammetry Glassy carbon electrode Pharmaceuticalformulation Nitazoxanide Squarewave voltammetry Glassy carbon electrode Pharmaceuticalformulation
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