非毒性结节性甲状腺肿和孤立性结节患者甲状腺乳头状癌风险比较

Comparing the risk of papillary thyroid carcinoma between patients with nontoxic multinodular goiter and solitary nodule

比较非毒性结节性甲状腺肿（nontoxicmultinodulargoiter，MNG）和孤立性甲状腺结节（solitarynodule，SN）患者甲状腺乳头状癌（papillarythyroidcarcinoma，PTC）发生率。761例在本院进行甲状腺手术的患者根据病理学诊断结果分为两组，MNG组和sN组。MNG组患者PTC发生率显著低于sN组患者（7．09％对15．58％，P=O．0009）。非毒性结节性甲状腺肿患者PTC发生率显著低于孤立性结节患者。

To investigate the risk of ＂papillary thyroid carcinoma （PTC） in patients with nontoxic muhinodular goiter （MNG） compared to that in patients with solitary nodule （SN）. From Jan 2006 to Dec 2011,761 patients underwent thyroid surgery were included in the retrospective study. According to pathology, patients were subdivided into two groups, MNG and SN. Preoperative thyroid profiles were correlated with patients＇ postoperative diagnoses. In whole group, the risk of PTC was significantly lower in MNG than in SN （7.09% vs 15.58% , P = 0. 000 9 ）. In patients with nontoxic multinodular goiter, the risk of PTC was lower compared to that of those with SN.