摘要
肾素-血管紧张素系统(renin—angiotensinsystem,RAS)是一个激素系统,当大量失血或血压下降时,这个系统会被启动,用以协调体内的长期血压与细胞外液量(体液平衡)。
Estrogen improves the pathological changes of the local tissues and organs and recovers the tissue function by regulating the activity of tissue renin-angiotensin system (RAS) and the expression of RAS components in the local tissues such as heart, blood vessel, kidney, adrenal gland, brain and skeleton. Therefore, tissue RAS is the biologi- cal regulating targets of estrogen. Here we review the pathophysiological roles of estrogen in the local tissue RAS by analy- zing and summarizing the recent researches.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2013年第12期2287-2291,共5页
Chinese Journal of Pathophysiology
基金
上海市教育委员会科研创新项目(No.11ZZ137)
上海市科学技术委员会资助(No.10PJ1407700)