溃疡性结肠炎患者营养风险评估及疗效评价

Evaluation of Nutritional Supports on Treatment of Ulcerative Colitis

目的评估溃疡性结肠炎患者营养风险、营养支持及疗效。方法 56例溃疡性结肠炎患者入院后进行营养风险筛查2002(NRS 2002)评估营养状况。营养支持分2组:溃疡性结肠炎综合治疗和肠内营养+肠外营养;综合治疗+肠内营养。监测0-4周营养指标变化,评价临床疗效。结果 50%以上患者存在营养风险。综合治疗+肠内和肠外营养方案改善消化系统功能及营养治疗指标效果好,显效率高于肠内营养组(P<0.05)。结论重度溃疡性结肠炎患者营养风险发生率较高,综合治疗的同时肠内+肠外营养支持疗效最好,应鼓励患者适量进食。

Objective To assess the nutritional status and the therapeutic effect of nutritional support on patients with ulcerative colitis. Methods Fifty-six ulcerative colitis patients received nutritional assessment by means of the nutritional risk score （NRS） 2002 after admitted into hospital. The patients were divided into treatment group and control group and changes in their nutritional condition were assessed. Results The UC, a recurrent type, was severer in treatment group than in control group and the number of UC patients with their whole colon involved was greater than that of those with their partial colon in- volved. The BMI and total protein level were significantly lower in control group after routine clinical treatment than in treat- ment group after combined simple clinical and individualized nutritional support treatment （ P 〈 0. 05）. Conclusion Most of the patients with ulcerative colitis have malnutrition. Enteral nutrition combined with parenteral nutrition showed the best effect on these patients, so that we should encourage patients to take more food if possible.