健康青壮年男性前列腺体积的经腹超声测定研究

Transabdominal ultrasound determination of prostate volume in healthy adult males

目的探讨健康青壮年男性（18～49岁）的前列腺体积变化趋势，分析影响前列腺体积的相关因素，为前列腺增生的临床诊断提供参考。方法选取18~49岁健康青壮年男性志愿者，记录其吸烟及饮酒情况，测量体重、身高，计算体重指数，采用经腹超声测定前列腺左右径、前后径、上下径，并计算前列腺体积。根据年龄将被调查者分为18-29岁、30-39岁、40-49岁3组。结果共计618例符合条件的健康男性纳入本项研究，平均前列腺体积为（16．83±4．84）cm3。其中，30岁以下青年男性的平均前列腺体积为（15．01±3．95）cm3。方差分析显示不同年龄段男性前列腺各径线和前列腺体积差异显著（P〈0．01），同时各组超重者（体质指数≥24kg/m2）的前列腺体积与体重正常者比较显著增大（P〈O．01）。饮酒与吸烟对前列腺体积变化无显著影响。Pearson相关分析显示，前列腺体积与年龄呈正相关（r=0．42，均P〈O．01），多元线性回归分析显示，前列腺体积受年龄、体重指数因素的影响（P〈0．05），而不受吸烟、饮酒的影响。结论随着年龄的增长健康青壮年男性前列腺体积明显增大，体重超重也是影响健康青壮年男性前列腺生长的重要因素之一。

Objeetive To measure the size of prostate in healthy adult male volunteers by transabdominal ultrasound examination, and to analyze possible factors to affect the growth of prostate. Methods A number of 648 healthy male adults were involved in the study. The length, width, and height of the prostate were measured by transabdominal ultrasound examination, and the prostate volume was calculated. All volunteers were divided into three groups according to their age, 18-29 years old group, 30-39 years old group, and 40-49 years old group. In addition, the personal data of all volunteers were recorded, including the age, weight, height, smoking and alcohol consumption. Results The average prostate volume was （16.83_＋4.84）em3 in 618 healthy male adults. There were significant differences in the value of the length, the height, the width of the prostate, and also in the prostate volume among the three different age groups（P〈0.01）. A significant increase in the prostate volume was noted in the overweight volunteers（P〈0.01）. Pearson correlation analysis showed that the prostate volume was significantly related to the age in this study（r=0.42, P〈0.01）. Conclusion With increasing of age, the prostate volume enlarged obviously in healthy adult males, and overweight may be an important factor to affect the prostate growth.