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非小细胞肺癌分子靶向治疗新靶点c-Met的研究进展 被引量:3

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摘要 一、简介 分子靶向治疗的快速发展,对于非小细胞肺癌(non.small.celllungcancer,NSCLC)的治疗具有革命性意义。近几年来,关于NSCIA2先天及后天致瘤因素的研究发展迅速,针对基因突变(先天致瘤因素)的单克隆抗体及小分子抑制剂则为临床提供了化疗之外的另一种重要治疗手段。近年来,
作者 李扬 于忠和
出处 《中华临床医师杂志(电子版)》 CAS 2013年第19期116-117,共2页 Chinese Journal of Clinicians(Electronic Edition)
基金 国家自然科学基金(81372489)
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  • 1Felsher DW,Bishop JM. Reversible tumorigenesis by MYC in hematopoietic lineages[J].Molecules and Cells,1999.199-207.
  • 2Chin L,Tam A,Pomerantz J. Essential role for oncogenic Ras in tumour maintenance[J].NATURE,1999.468-472.
  • 3Jain M,Arvanitis C,Chu K. Sustained loss of a neoplastic phenotype by brief inactivation of MYC[J].SCIENCE,2002,(5578):102-104.doi:10.1126/science.1071489.
  • 4Huettner CS,Zhang P,Van Etten RA. Reversibility of acute B-cell leukaemia induced by BCR-ABL1[J].Nature genetics,2000.57-60.
  • 5Pelengaris S,Khan M,Evan GI. Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression[J].CELL,2002.321-334.
  • 6Sharma A,Trivedi NR,Zimmerman MA. Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors[J].CANCER RESEARCH,2005.2412-2421.
  • 7Weinstein IB,Joe AK. Mechanisms of disease:Oncogene addiction--a rationale for molecular targeting in cancer therapy[J].ONCOLOGY,2006.448-457.
  • 8Shaw AT,Yeap BY,Solomon BJ. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement:a retrospective analysis[J].LANCET ONCOLOGY,2011.1004-1012.
  • 9Bergethon K,Shaw AT,Ou SH. ROS1 rearrangements define a unique molecular class of lung cancers[J].Journal of Clinical Oncology,2012.863-870.
  • 10West L,Vidwans SJ,Campbell NP. A novel classification of lung cancer into molecular subtypes[J].PLoS One,2012.e31906.

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