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二维跨壁纵向应变率评价冠心病患者心肌功能 被引量:1

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摘要 目的探讨采用二维斑点追踪技术(STI)检测心肌跨壁纵向应变率(LSR)参数来评价不同程度冠状动脉狭窄对心肌功能的影响。方法对31例可疑冠心病患者进行超STI检查,根据冠状动脉造影结果,将心肌节段分为4组:正常心肌组、轻度狭窄心肌组、中度狭窄心肌组、重度狭窄心肌组。测量心内膜下(subendocardial,endo)心肌收缩期纵向应变率(LSRs-endo)、舒张早期纵向应变率(LSRe-endo)和舒张晚期纵向应变率(LSRa-endo)及心外膜下(subepicardial,epi)心肌纵向应变率(LSRs-epi、LSRe-epi、LSRa-epi),分别计算跨壁应变率LSRs-mural、LSRe-mural及LSRa-mural。4组间各参数进行比较。结果 (1)正常心肌组与轻度狭窄心肌组各参数无明显差异;(2)中度狭窄心肌组、重度狭窄心肌组LSRs-endo、LSRs-epi、LSRe-endo、LSRe-epi及LSRa-endo与正常心肌组比均减低(P<0.001);重度狭窄心肌组LSRa-epi与正常心肌组比减低(P<0.01)。(3)中度狭窄心肌组LSRe-mural与正常心肌组比减低(P<0.05)。结论冠状动脉狭窄程度大于50%时心肌功能已损伤,二维跨壁纵向应变率能够早期检测心肌功能改变。
出处 《中华临床医师杂志(电子版)》 CAS 2013年第19期131-132,共2页 Chinese Journal of Clinicians(Electronic Edition)
基金 辽宁省科技厅科学计划项目(2011225020)
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