医院抗肿瘤药物处方分析

Analysis of anti-neoplastic drugs prescriptions

目的分析广州市中西医结合医院静脉配置抗肿瘤药物临床应用现状。方法依据药物法定说明书及相关药学资料对我院静脉配置抗肿瘤药物处方3625张进行统计分析。结果在静脉配置抗肿瘤药物处方3625张中存在不合理用药问题的处方为105张，占2．9％。其中选用不合理溶媒占不合理用药处方的42．8％（45／105），给药浓度不合理占33．3％（35／105），溶媒用量不合理占13．3％（14／105），给药剂量不合理占7．6％（8／105），给药方式不合理占2．9％（3／105）。结论我院静脉配置抗肿瘤药物临床用药存在不合理情况。应加强医生对用药知识的了解和临床药师的审核与把关。建立静脉配置抗肿瘤药物合理用药规范，对提高我院的合理用药水平有重要意义。

Objective To analyze the clinical application of anti-neoplastic drugs of pharmacy intravenous admixture services（PIVAS）. Methods The prescriptions of anti-neoplastic from PIVAS in our hospital were analyzed according to the statutory instructions and related drugs pharmacy information. Results Among 3625 antineoplasite drugs prescriptions in PIVAS, the irrational usage of drugs was 105 cases （2.9%） ; unreasonablesolvent accounted for 42.8% （45/105） with irrational drug concentration（33.3% , 35/105 ） plus solvent dosage（ 13.3% , 14/105） plus administered dose（7.6% , 8/105） and mode of administration（2.9% , 3/105 ）. Conclusions The clinical application of anti-neoplastic drugs is unreasonable. It is important to establish reasonable Medication specification of anti-neoplastic drugs and improve the rational usage of anti-neoplastic drugs.