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EZSCAN^(TM)检测糖尿病风险新技术在2型糖尿病中的应用 被引量:2

EZSCANTM New Technology for Type 2 Diabetes Risk Detection
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摘要 目的:通过对比试验评估EZSCAN在2型糖尿病患者中的灵敏度和特异度。方法:筛选长期来中心体检且已诊断患有2型糖尿病2~3 a病史但无并发症,且本次空腹血糖>7.0 mmol/L的64例患者;筛选56例健康对象,空腹血糖低于6.11 mmol/L,且经常运动,无直系亲属患有糖尿病。对这120人进行问卷调查、体格检查、空腹血糖检查和EZSCAN测量。结果:糖尿病患者的手、脚ESC(电化学汗液电导率)显著降低(37.5±20.4)、(48.6±19.2)、(46.3±18.5)和(39.0±20.1)μSi,健康人群的手、脚ESC分别为(58.6±17.2)、(75.2±13.9)、(86.8±7.9)和(71.2±10.2)μSi,P<0.0001。糖尿病患者的手和脚的电化学汗液电导率明显低于健康人,其灵敏度和特异度分别为78.1%和100%。结论:EZSCAN具有高灵敏度和敏感度,可以快速、无创地通过电化学皮肤电导的测量精确评估糖尿病患者的汗腺功能。 Objective To assess the sensitivity and specificity of EZSCAN method for type 2 diabetes risk detection. Methods The subjects included 64 type 2 diabetic patients with histories of 2 to 3 years, fasting blood glucose more than 7.0 mmol/L and no complications, as well as 56 healthy ones with fasting blood glucose less than 6.11 mmol/L, regular exercise and no direct relative with diabetes. Then the 120 ones underwent questionnaire, physical examination, fasting blood glucose detection and EZSCAN measurement. Results The ESCs of the hands and feet of the patients were reduced greatly, which were(37.5±20.4),(48.6±19.2),(46.3±18.5) and(39.0±20.1)μSi respectively; those of the healthy ones were (58.6±17.2), (75.2±13.9), (86.8±7.9) and (71.2±10.2)μSi, with P〈0.0001. The ESCs of the hands and feet of the patients were significantly lower than those of the healthy ones, and the sensitivity and specificity were 78.1% and 100% respectively. Conclusion EZSCAN has a high sensitivity and specificity, and can be used to detect the sweat gland function of the diabetes patient by measuring ESC.
机构地区 解放军
出处 《医疗卫生装备》 CAS 2013年第12期78-79,87,共3页 Chinese Medical Equipment Journal
关键词 EZSCAN 2型糖尿病 空腹血糖 EZSCAN type 2 diabetics fasting plasma glucose
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参考文献13

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