期刊文献+

分层解剖在根治性胰十二指肠切除术中的应用

Sequential layered dissection in radical pancreatoduodenectomy
下载PDF
导出
摘要 目的:探讨分层解剖在根治性胰十二指肠切除术中的应用价值和临床疗效。方法:我科自2010年3月~2012年10月共行胰十二指肠切除术16例,现回顾分析分层解剖根治手术的临床资料。结果:本组16例患者均顺利完成手术,平均手术时间(6.5±0.2)h,平均术中出血量约(200±30)ml,平均淋巴结清除数(24.2±1.4)个,平均淋巴结阳性数(3.6±1.2)个;平均住院日(22±1.5)d,术后切口均甲级愈合,1例出现胰肠吻合口瘘。结论:分层解剖在根治性胰腺十二指肠切除术中可以进行程序化解剖清扫淋巴脂肪组织,减少手术时间和术中出血量,降低术中血管骨骼化清扫难度,值得临床推广应用。 Objective:To investigate the clinical value of applying se-quential layered dissection route to radical pancreatoduodenectomy . Methods: The clinical data were reviewed in 16 patients undergone pan-creatoduodenectomy between March 2010 and October 2012 in our depart-ment.Results: The total 16 patients went through successful operation . The mean operative time was 6.5 h,and mean intraoperative blood loss 200 ml.Dissection of the total number of lymph node and positive lymph node was respectively 24.2 and 3.6 on average.Average hospital stay was 22 days,and the total patients achieved level-A would healing after proce-dure except for occurrence of anastomosis fistula in one case.Conclusion:Applying sequential layered dissection route to radical pancreatoduode-nectomy may lead to standardized dissection of the lymph nodes ,reduced operative time and intraoperative blood loss as well as easy clearing of skeletonization of the vasculature in operation , which is worthy of wider clinical recommendation.
出处 《皖南医学院学报》 CAS 2013年第6期456-459,共4页 Journal of Wannan Medical College
关键词 分层解剖 根治性胰十二指肠切除术 sequential layered dissection radical pancreatoduodenec-tomy
  • 相关文献

参考文献20

  • 1赵玉沛.胰腺癌诊治存在的问题与争议[J].中华消化外科杂志,2007,6(4):249-251. 被引量:18
  • 2张太平,肖剑春,赵玉沛.NCCN胰腺癌外科治疗指南解读[J].临床肝胆病杂志,2010,26(5):454-458. 被引量:10
  • 3赵玉沛.胰腺癌诊治指南[J].中国实用外科杂志,2007,27(9):671-673. 被引量:48
  • 4LIPPINCOTT WILLIAMS,WILKINS,Baker R J,Fisher J E. Mastery of Surgery[M].USA,2001.1299-1316.
  • 5ISHIKAWA O. Surgical technique,curability and postoperative quality of life in an extended pancreatectomy for adenocarcinoma of the pancreas[J].{H}Hepato-Gastroenterology,1996,(08):320-325.
  • 6JEMAL A,SIEGEL R,WARD E. Cancer statistics,2007[J].{H}CA-A Cancer Journal for Clinicians,2007,(01):43-66.
  • 7CARPELAN-HOLMSTMM M,NORDLING S,PUKKALA E. Does anyone survive pancreatic ductal adenocarcinoma? A nation-wide study re-evaluating the data of the Finnish Cancer Resistry[J].{H}GUT,2005,(03):385-387.
  • 8BOGOEVSKI V,YEKEBAS E,SCHURR P. Mode of spread in the early phase of lymphatic metastasis in pancreatic ductal ade-nocarcinoma:prognostic significance of nodal microinvolvement[J].Ann Srug,2004,(06):993-1001.
  • 9NAKAO A,HARADA A,NONAMI T. Lymph node metasta-ses in carcinoma of the head of the pancreas region[J].{H}British Journal of Surgery,1995,(03):399-402.
  • 10DAI H,LI R,WHEELER T. Enhanced survival in the peri-neural invasion of pancreatic cancer:an in vitro approach[J].{H}Human Pathology,2007,(02):299-307.

二级参考文献76

  • 1Jemal A, Siegel R, Ward E,et al. Cancer statistics, 2009[J]. CA Cancer J Clin, 2009, 59 (4) : 225 - 249.
  • 2Crist DW, Sitzmann JV, Cameron JL. Improved hospital morbidity, mortality, and survival after the Whipple procedure[ J]. Ann Surg, 1987, 206 (3) : 358 - 365.
  • 3Li D, Xie K, Wolff R, et al. Pancreatic cancer [ J]. Lancet, 2004, 363:1049 - 1057.
  • 4Bipat S, Phoa SS, van Delden OM, et al. Ultrasonography, computed tomography and magnetic resonance imaging for diagnosis and determining resectability of pancreatic adenocarcinoma: a meta - analysis[ J ]. J Comput Assist Tomogr, 2005, 29 (4) : 438 - 445.
  • 5National Comprehensive Cancer Network (NCCN) Clinical Practice Guideline in Oncology for Pancreatic Adenocarcinoma V [ S ]. 1. 2009.
  • 6Katz MH, Pisters PW, Evans DB, et al. Borderline resectable pancreatic cancer: the importance of this emerging stage of disease[ J]. J Am Coll Surg, 2008, 206 (5) : 833 - 846.
  • 7Evans DB, Varadhachary GR, Crane CH, et al. Preoperative gemcitabine- based chemoradiation for patients with resectable adenocarcinoma of the pancreatic head[ J]. J Clin Oncol, 2008,26: 3496 - 3502,.
  • 8Gillen S, Schuster T, Meyer ZC, et al. Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta- analysis of response and resection percentages[ J]. PLoS Med, 2010, 7 (4): e1000267.
  • 9McClaine R J, Lowy AM, Sussman J J, et al. Neoadjuvant therapy may lead to successful surgical resection and improved survival in patients with borderline resectable pancreatic cancer [ J ]. HPB ( Oxford), 2010, 12 ( 1 ) : 73 - 79.
  • 10Landry J, Catalano P J, Staley C, et al. Randomized phase II study of gemcitabine plus radiotherapy versus gemcitabine, 5 - fluorouracil, and cisplatin followed by radiotherapy and 5 - fluorouracil for patients with locally advanced, potentially resectable pancreatic adenocarcinoma[ J]. J Surg Oncol, 2010, 101 (7) : 587 - 592.

共引文献86

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部