143例巨细胞病毒感染婴幼儿的肝肾功能观察

Observation of liver and renal function in 143 Infants Sinfected with HCMV

目的探讨人巨细胞病毒(human cytomegalovirus,HCMV)感染对婴幼儿肝肾功能的影响。方法回顾性分析143例HCMV感染的婴幼儿的肝肾功能指标,并与对照组比较,实验数据采用SPSS15.0统计软件处理并进行分析。结果观察组肝肾功能指标丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、r-谷氨酰转移酶(GGT)、血肌酐(Scr)均高于对照组,差异均有统计学意义(P值=0.000～0.05)。肝功能异常发生率为76.22%,肾功能异常发生率为6.99%。结论婴幼儿HCMV感染时多数存在肝功能损害,部分存在肾功能损害,诊治时应注意监测和保护肝肾功能。

Objective To investigate the influence of HCMV infection on infants＇ liver and renal functions. Methods The indexes of liver and renal functions were retrospectively analyzed in 143 infants swith HCMV infection,then making a comparison with the control group. The experimental data were processed by SPSS15.0 statistical software. Results The indexes of liver and renal functions included ALT, AST, GGT and Set. All the indexes in the observation group were higher than the control group,and the differences showed statistical significance （/9=-0.000-0.05）. The incidence rate of abnormal liver function was 76.22% ,while the incidence rate of abnormal renal function was 6.99%. Conclusions The infants suffered from HCMV infection mostly had liver function damage, some had renal function damage. Thus it＇s important to monitor and protect the liver and renal function.