卡泊三醇治疗播散性浅表性汗孔角化病1例并文献复习

Successful treatment of disseminated superficial porokeratosis with calcipotriol and review of the literature

播散性浅表性汗孔角化病(disseminated superficial porokeratosis,DSP)是一种较少见的慢性进行性角化性皮肤病。其皮损广布于光暴露部位,表浅播散。该病常用的治疗方法包括维A酸,光动力疗法,氟尿嘧啶(5-FU),CO_2激光等,但疗效均不能令人满意。笔者诊治1例DSP患者,使用卡泊三醇软膏治疗3个月后皮损明显好转。

Disseminated superficial porokeratosis （DSP） is a chronic disorder of keratinization characterized by numerous papules and plaques distributed over sun-exposed sites. The efficiency of current treatment regimens for DSP, including tretinoin, photodynamic therapy, 5-fluorouracil, C02 laser and so on, is limited. A report a case of whose lesions is reported and improved after topical applications of vitamin D3 analog calcipotriol.