消瘰合剂治疗淋巴结结核30例

Xiaolei Mixture(消瘰合剂) in Treating 30 Cases of Lymph Node Tuberculosis

目的观察自拟方消瘰合剂治疗各型瘰疬(淋巴结结核)疗效。方法将60例瘰疬(淋巴结结核)患者随机分成治疗组及对照组,各30例。治疗组以自拟方消瘰合剂(黄芪、玄参、黄精、猫爪草、百部等,1剂/d,2/d)加西药[3RHE/6RH(3个月的异烟肼0.3 g,1次/d,利福平0.45 g,1次/d,乙胺丁醇0.75 g,1次/d强化治疗及6个月的异烟肼0.3 g,1次/d,利福平0.45 g,1次/d巩固治疗)]抗结核;对照组予传统西药抗结核(3RHE/6RH),30 d为1个疗程,每个疗程结束为1观察周期。通过2个观察周期,统计2组总有效率及低热、盗汗、咳嗽等结核典型临床表现例数。结果 2个疗程后治疗组总有效率100%,对照组90%,2组比较P<0105,有统计学意义;第1疗程结束对于低热、盗汗、咳嗽等结核典型临床表现,缓解例数治疗组明显优于对照组。结论传统西药加本方治疗后能明显提高疗效,同时缩短患者低热、盗汗等全身症状改善时间。

Objective To observe the effect of self-made Xiaolei Mixture on treating scrofula （tuberculosis of lymph nodes）. Methods 60 patients with scrofula （tuberculosis of lymph nodes） were randomly divided into treatment group and the control group. 30 cases in each group. Patients in treatment group were treated with self-made Xiaolei Mixture （born Astragalus, Figwort, Sealwort, cat claw grass, and Stemona, 1 dose/day,2 times/day） and western medicine [3RHE/6RH （isoniazid for 3 months,0.3 g, 1/day, rifampicin 0.45 g, 1/day, ethylamine butanol for strengthening treatment 0.75 g, 1/day and the isoniazid for 6 months, 0.3 g, 1/day and rifampicin for consolidating treatment 0.45 g, 1/day）] as anti-TB drugs. Patients in control group were treated with traditional Western anti-TB drug （3RHE/6RH） ,30 days for a course of treatment. Each course ends for theobservation cycle. Through 2 cycles of observation, we summarized the case numbers of total effective rate, low fever, night sweats and coughs which are typical clinical manifestations of TB in two groups. Result After 2 courses oftreatment, the total effective rate in the treatment group is 100% and 90% in the control group （P 〈 0. 05）. It has statistical significance; After the completion of the first course for typical clinical manifestations of TB, such as low-grade fever, night sweats, cough, relieve cases of treatment groups were significantly better than that of the control group. Conclusion Traditional Western medicine and this treatment can significantly improve the efficacy and shorten the time of systemic symptoms such as low-grade fever, night sweats in patients.