坤泰胶囊治疗女性更年期失眠伴有焦虑及抑郁的临床观察

Clinical observation of Kuntai Capsule on female menopause insomnia associated with anxiety and depression

目的观察坤泰胶囊治疗女性更年期失眠且伴有焦虑及抑郁的临床疗效。方法将120例患有更年期失眠并伴有焦虑及抑郁的女性患者分为两组,治疗组60例采用中成药坤泰胶囊治疗,对照组60例口服舒乐安定片,10 d为1个疗程,2个疗程后,观察两组患者的临床疗效及睡眠质量、焦虑和抑郁改善情况。结果治疗组睡眠、焦虑改善情况与对照组比较差异不显著(P>0.05);睡眠质量改善与对照组比较差异显著(P<0.05);抑郁改善情况明显优于对照组(P<0.01)。结论坤泰胶囊治疗女性更年期失眠伴有焦虑、抑郁有较好的临床疗效。

Objective To observe the clinical curative effect of Kuntai Capsule on female menopause insomnia associated with anxiety and depression. Methods Women patients （120 cases） with menopausal insomnia accompanied by anxiety and depression were divided into control and treatment groups, 60 cases in each group. Kuntai Capsule was given to the patients in the treatment group, while oral Estazolam Tablets were given to the patients in the control group, both groups were treated for 10 d as one course of the treatment. After two periods of the treatment, the clinical efficacy for the improvement of sleep quality, anxiety, and depression of patients in the two groups was observed. Results Compared with the control group, there was no significant difference on the treatment of insomnia and anxiety between the treatment and control groups （P 〉 0.05）, while there was the significant difference on the improvement of sleep quality in the treatment group （P 〈 0.05） and the improvement of depression was better than that in the control group （P 〈 0.01）. Conclusion Kuntai Capsule has a good curative effect on the female menopause insomnia associated with anxiety and depression.