腹水超滤浓缩技术应用研究

Applied research on the ascites enrichment technology

目的:应用研发的腹水超滤治疗仪和腹水超滤技术进行顽固性腹水的临床观察研究。方法:采用腹腔对腹腔腹水浓缩回输技术对各类病因引起的顽固性腹水的647例患者进行治疗。结果:顽固性腹水患者平均治疗(2.8±1.5)次,治疗时间为(2.4±1.2)h/次;滤出腹水(8543±2427)ml/次,体重平均下降(8.4±2.4)kg;腹围由治疗前的(108.7±13.5)cm降低至(87.4±15.3)cm;24 h尿量明显增加,由治疗前的(257.8±235.6)ml增至(725.8±436.9)ml(t=3.147,P<0.01)。不良反应发生率为3.3%(63例/1892例次)。结论:腹腔对腹腔腹水浓缩回输技术方法简单,适应症广,且不良反应小,是一种治疗顽固性腹水有效的方法。

Objective： To apply the development of ascites ultrafiltration treatment instrument and ascites ultrafiltration technology for clinical observation research. Methods：By intraperitoneal on peritoneal ascites reinfusion of various causes of refractory ascites were treated. Results： A total of 647 cases of patients with refractory ascites, with the average for 2.8±1.5 times, treatment time 2.4±1.2 hours/times; filtering out ascites in 8543±2427 ml/times, lost an average of 8.4±2.4 kg; abdominal circumference decreased from 108.7 before treatment to 87.4±15.3 cm; 24 hour urine volume increased significantly, from 257.8±235.6 ml to 725.8±436.9 ml （P〈0.01）. The incidence of adverse reaction was 3.3%（63/1892 cases）. Conclusion：Abdominal peritoneal ascites reinfusion method is simple, wide indications, adverse reactions, is a kind of method for the treatment of intractable ascites effectively.