布地奈德雾化吸入联合机械振动排痰佐治毛细支气管炎疗效观察

Effect of budesonide atomization inhalation combined with mechanical vibration sputum in bronchiolitis

目的：探讨布地奈德混悬液（布地奈德）雾化吸入联合机械振动排痰佐治毛细支气管炎的疗效。方法125例毛细支气管炎患儿采用随机数表法分为治疗组（65例）和对照组（60例）。对照组在常规综合治疗基础上使用机械振动排痰治疗，5～10分钟/次，2次/天，疗程3～5 d ；治疗组给予雾化吸入布地奈德混悬液0．5毫克/次，5～10分钟/次，2次/天，联合机械振动排痰进行治疗，疗程3～5 d 。结果治疗组喘憋、哮鸣音、肺部啰音、咳嗽消失时间及住院时间均优于对照组，差异有统计学意义（ P＜0．01），治疗组和对照组总有效率分别为93．85％和81．67％，差异有统计学意义（ P＜0．05，χ2＝4．38）。结论布地奈德雾化吸入联合机械振动排痰辅助治疗毛细支气管炎安全有效。

Objective To observe the therapeutic effect of budesonide atomization inhalation with mechanical vibration sputum elimination for bronchiolitis .Methods One hundred and twenty -five cases with bronchiolitis were divided into treatment group（n= 65） and control group（n= 60）by a random number table method .The contrast group were treated with conventional treatment combined with atomization inhalation given 5-10 min/time ,2-3/d , for 3-5 d .The treatment group were treated with budesonide suspension （0 .5 mg each） with mechanical vibration sputum given 5-10 min/time ,2/d for 3-5 d .Results Compared with the control group ,the time of asthma relie-ving ,wheezing ,pulmonary rales ,and cough and the length of hospital days of the treatment group were significant shorter than those of the control group （P〈0 .01） .The total effective rate in treatment group （93 .85% ）was signifi-cant higher than that in the control group （81 .67% ） .The difference was significant （ P〈 0 .05 ,χ2 = 4 .38 ） . Conclusion The treatment of budesonide atomization inhalation with mechanical vibration sputum for bronchiolitis is a safe effective adjuvant therapy .