摘要
目的考察三黄散瘀巴布剂用药的安全性。方法家兔6只,随机平均分为两组,观察三黄散瘀巴布剂对家兔完整及破损皮肤的刺激反应;家兔36只,随机平均分为6组,观察三黄散瘀巴布剂对家兔完整及破损皮肤的急性毒性反应;豚鼠30只,随机平均分为3组,观察三黄散瘀巴布剂对豚鼠的皮肤变态反应。结果三黄散瘀巴布剂对家兔完整及破损皮肤无任何刺激性反应;家兔未出现任何急性毒性反应;豚鼠皮肤未见变态反应。结论三黄散瘀巴布剂安全无毒。
Objective To investigate the safety of sanhuang sanyu cataplasm. Methods Six rabbits were randomly divided into 2 groups. Skin irritation of sanhuang sanyu cataplasm on rabbits＇ complete and injured skin was observed. Thirty-six rabbits were randomly divided into 6 groups, acute toxicity of sanhuang sanyu cataplasm on injured and injured skin of rabbits was examined. Thirty guinea pigs were randomly divided into 3 groups. Allergic reaction from sanhuang sanyu cataplasm in guinea pig skin was observed. Results Sanhuang sanyu had no irritation and acute toxicity on complete or injured skin of rabbits. There was no allergic reaction in guinea pig skin. Conclusion Sanhuang sanyu cataplasm is safe and non-toxic.
出处
《医药导报》
CAS
北大核心
2013年第12期1574-1576,共3页
Herald of Medicine
基金
浙江省科技厅重点科技计划项目(2007C23020)
浙江省中药现代化专项资金(浙财企字[2008]268号)
浙江省中医药科研基金资助项目(2006C038)
关键词
三黄散瘀巴布剂
刺激性
皮肤
毒性
急性
皮肤
皮肤过敏
Sanhuang sanyu cataplasm
Irritation, skin
Toxicity, acute, skin
Skin allergies
